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Full TextIssue DateTitleAuthor(s)
2012Early-Onset Alcohol Dependence Increases the Acoustic Startle ReflexSchellekens, A.F.A.; Mulders, P.C.R.; Ellenbroek, B.A.; Jong, C.A.J. de; Buitelaar, J.K.; Cools, A.R.; Verkes, R.J.
2012Reduced Dopamine Receptor Sensitivity as an Intermediate Phenotype in Alcohol Dependence and the Role of the COMT Val158Met and DRD2 Taq1A GenotypesSchellekens, A.F.A.; Franke, B.; Ellenbroek, B.A.; Cools, A.R.; Jong, C.A.J. de; Buitelaar, J.K.; Verkes, R.J.
2011Schizophrenia endophenotypes and stress hyper-reactivity co-precipitate following adverse life events in genetically susceptible ratsDaskalakis, N.P.; Martens, G.J.M.; Cools, A.R.; Kloet, E.R.
2011Reserpine differentially affects cocaine-induced behavior in low and high responders to noveltyVerheij, M.M.M.; Cools, A.R.
2010Blockade of dopamine, but not noradrenaline, transporters produces hyperthermia in rats that lack serotonin transporters.Olivier, J.D.A.; Cools, A.R.; Deen, P.M.T.; Olivier, B.; Ellenbroek, A.A.
2010Dopamine D-like receptors play only a minor role in the increase of striatal dopamine induced by striatally applied SKF38393.Sekino, R.; Saigusa, T.; Aono, Y.; Uchida, T.; Takada, K.; Oi, Y.; Koshikawa, N.; Cools, A.R.
2010Differential role of GABAA and GABAB receptors in two distinct output stations of the rat striatum: studies on the substantia nigra pars reticulata and the globus pallidus.Ikeda, H.; Kotani, A.; Koshikawa, N.; Cools, A.R.
2009Mesolimbic alpha-, but not beta-adrenoceptors control the accumbal release of dopamine that is derived from reserpine-sensitive storage vesiclesVerheij, M.M.M.; Cools, A.R.
2009Accumbal noradrenaline that contributes to the alpha-adrenoceptor-mediated release of dopamine from reserpine-sensitive storage vesicles in the nucleus accumbens is derived from alpha-methyl-para-tyrosine-sensitive poolsVerheij, M.M.M.; Cools, A.R.
2009Individual differences in the sensitivity to serotonergic drugs: a pharmacobehavioural approach using rats selected on the basis of their response to noveltyVerheij, M.M.M.; Veenvliet, J.V.; Kormelink, T.G.; Steenhof, M.; Cools, A.R.
2009Serotonin transporter deficiency in rats contributes to impaired object memoryOlivier, J.D.A.; Jans, L.A.W.; Blokland, A.; Broers, N.J.; Homberg, J.R.; Ellenbroek, B.A.; Cools, A.R.
2009The dopamine agonist apomorphine differentially affects cognitive performance in alcohol dependent patients and healthy controls.Schellekens, A.F.A.; Oosterwijck, A.W.A.A.; Ellenbroek, A.A.; Jong, C.A.J. de; Buitelaar, J.K.; Cools, A.R.; Verkes, R.J.
2009Somatostatin receptors in the nucleus accumbens modulate dopamine-dependent but not acetylcholine-dependent turning behaviour of rats.Ikeda, H.; Kotani, A.; Koshikawa, N.; Cools, A.R.
2009Individual differences in the sensitivity to serotonergic drugs: a pharmacobehavioural approach using rats selected on the basis of their response to novelty.Verheij, M.M.M.; Veenvliet, J.V.; Groot Kormelink, T.; Steenhof, M.; Cools, A.R.
2009Accumbal noradrenaline that contributes to the alpha-adrenoceptor-mediated release of dopamine from reserpine-sensitive storage vesicles in the nucleus accumbens is derived from alpha-methyl-para-tyrosine-sensitive pools.Verheij, M.M.M.; Cools, A.R.
2009Mesolimbic alpha-, but not beta-adrenoceptors control the accumbal release of dopamine that is derived from reserpine-sensitive storage vesicles.Verheij, M.M.M.; Cools, A.R.
2009The dopamine agonist apomorphine differentially affects cognitive performance in alcohol dependent patients and healthy controlsSchellekens, A.F.A.; Oosterwijck, A.W.A.A.; Ellenbroek, A.A.; Jong, C.A.J. de; Buitelaar, J.K.; Cools, A.R.; Verkes, R.J.
2009Serotonin transporter deficiency in rats contributes to impaired object memory.Olivier, J.D.A.; Jans, L.A.W.; Blokland, A.; Broers, N.J.; Homberg, J.R.; Ellenbroek, A.A.; Cools, A.R.
2009GABAA receptors in the mediodorsal thalamus play a crucial role in rat shell-specific acetylcholine-mediated, but not dopamine-mediated, turning behaviour.Ikeda, H.; Kotani, A.; Lee, J.; Koshikawa, N.; Cools, A.R.
2009Contribution of vesicular and cytosolic dopamine to the increased striatal dopamine efflux elicited by intrastriatal injection of SKF38393.Saigusa, T.; Aono, Y.; Sekino, R.; Uchida, T.; Takada, K.; Oi, Y.; Koshikawa, N.; Cools, A.R.
2008Reduced splenic natural killer cell activity in rats with a hyperreactive dopaminergic systemTeunis, M.A.T.; Heijnen, C.J.; Cools, A.R.; Kavelaars, A.M.A.A.
2008Rats that differentially respond to cocaine differ in their dopaminergic storage capacity of the nucleus accumbens.Verheij, M.M.M.; Mulder, E.L.W. de; Leonibus, E. de; Loo, K.M.J. van; Cools, A.R.
2008Schrijfkramp : herstel van striatale dopaminerge activiteit na succesvolle behandeling met EMG-biofeedbackBerger, H.J.C.; Werf, S.P. van der; Horstink, C.A.; Cools, A.R.; Oyen, W.J.G.; Horstink, M.W.I.M.
2008Role of GABA B receptors in the endomorphin-1-, but not endomorphin-2-, induced dopamine efflux in the nucleus accumbens of freely moving rats.Saigusa, T.; Aono, Y.; Mizoguchi, N.; Iwakami, T.; Takada, K.; Oi, Y.; Ueda, K.; Koshikawa, N.; Cools, A.R.
2008Role of orexin receptors in the nucleus accumbens in dopamine-dependent turning behaviour of rats.Kotani, A.; Ikeda, H.; Koshikawa, N.; Cools, A.R.
2008Twenty years of dopamine research: individual differences in the response of accumbal dopamine to environmental and pharmacological challenges.Verheij, M.M.M.; Cools, A.R.
2008The reboxetine-induced increase of accumbal dopamine efflux is inhibited by l-propranolol: a microdialysis study with freely moving rats.Mizoguchi, N.; Saigusa, T.; Aono, Y.; Sekino, R.; Takada, K.; Oi, Y.; Ueda, K.; Koshikawa, N.; Cools, A.R.
2008Behavioural characterisation of rats exposed neonatally to bisphenol-A: responses to a novel environment and to methylphenidate challenge in a putative model of attention-deficit hyperactivity disorder.Kiguchi, M.; Fujita, S.; Oki, H.; Shimizu, N.; Cools, A.R.; Koshikawa, N.
2008Role of GABAA receptors in the endomorphin-1-, but not endomorphin-2-, induced dopamine efflux in the nucleus accumbens of freely moving rats.Aono, Y.; Saigusa, T.; Mizoguchi, N.; Iwakami, T.; Takada, K.; Gionhaku, N.; Oi, Y.; Ueda, K.; Koshikawa, N.; Cools, A.R.
2008Neural correlates of strategic memory retrieval: differentiating between spatial-associative and temporal-associative strategies.Rover, M de; Petersson, K.M.; Werf, S.P. van der; Cools, A.R.; Berger, H.J.C.; Fernandez, G.
2008Stress-induced hyperthermia and basal body temperature are mediated by different 5-HT(1A) receptor populations: a study in SERT knockout rats.Olivier, J.D.A.; Cools, A.R.; Olivier, B.; Homberg, J.R.; Cuppen, E.; Ellenbroek, B.A.
2008Acute tryptophan depletion dose dependently impairs object memory in serotonin transporter knockout rats.Olivier, J.D.A.; Jans, L.A.; Korte-Bouws, G.A.; Korte, S.M.; Deen, P.M.T.; Cools, A.R.; Ellenbroek, B.A.; Blokland, A.
2008Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats.Homberg, J.R.; Boer, SF De; Raaso, H.S.; Olivier, J.D.A.; Verheul, M.; Ronken, E.; Cools, A.R.; Ellenbroek, B.A.; Schoffelmeer, A.N.; Schuren, L.J. van der; Vries, TJ De; Cuppen, E.
2008A study in male and female 5-HT transporter knockout rats: an animal model for anxiety and depression disorders.Olivier, J.D.A.; Hart, MG Van Der; Swelm, R.P.L. van; Dederen, P.J.W.C.; Homberg, J.R.; Cremers, T.; Deen, P.M.T.; Cuppen, E.; Cools, A.R.; Ellenbroek, B.A.
2007Differential contribution of storage pools to the extracellular amount of accumbal dopamine in high and low responders to novelty: effects of reserpine.Verheij, M.M.M.; Cools, A.R.
2007Role of alpha adrenoceptors in the nucleus accumbens in the control of accumbal noradrenaline efflux: a microdialysis study with freely moving rats.Aono, Y.; Saigusa, T.; Watanabe, S.; Iwakami, T.; Mizoguchi, N.; Ikeda, H.; Ishige, K.; Tomiyama, K.; Oi, Y.; Ueda, K.; Rausch, W.D.; Waddington, J.L.; Ito, Y.; Koshikawa, N.; Cools, A.R.
2007Role of caspase-12 in amyloid beta-peptide-induced toxicity in organotypic hippocampal slices cultured for long periods.Ishige, K.; Takagi, N.; Imai, T.; Rausch, W.D.; Kosuge, Y.; Kihara, T.; Kusama-Eguchi, K.; Ikeda, H.; Cools, A.R.; Waddington, J.L.; Koshikawa, N.; Ito, Y.
2007Characterization of the serotonin transporter knockout rat: a selective change in the functioning of the serotonergic system.Homberg, J.R.; Olivier, J.D.A.; Smits, B.M.; Mul, J.D.; Mudde, J.; Verheul, M.; Nieuwenhuizen, O.F.; Cools, A.R.; Ronken, E.; Cremers, T.; Schoffelmeer, A.N.; Ellenbroek, B.A.; Cuppen, E.
2007Effects of acute and chronic apomorphine on sex behavior and copulation-induced neural activation in the male rat.Olivier, J.D.A.; Jong, T.R. de; Dederen, P.J.W.C.; Oorschot, R. van; Heeren, D.J.; Pattij, T.; Waldinger, M.D.; Coolen, L.M.; Cools, A.R.; Olivier, B.; Veening, J.G.
2007Writer's cramp: restoration of striatal D2-binding after successful biofeedback-based sensorimotor training.Berger, H.J.C.; Werf, S.P. van der; Horstink, C.A.; Cools, A.R.; Oyen, W.J.G.; Horstink, M.W.I.M.
2007A vehicle injection into the right core of the nucleus accumbens both reverses the region-specificity and alters the type of contralateral turning elicited by unilateral stimulation of dopamine D2/D3 and D1 receptors in the left core of the nucleus accumbens.Ikeda, H.; Kotani, A.; Koshikawa, N.; Cools, A.R.
2007Differences in the cellular mechanism underlying the effects of amphetamine on prepulse inhibition in apomorphine-susceptible and apomorphine-unsusceptible rats.Elst, M.C.J. van der; Wunderink, Y.S.; Ellenbroek, B.A.; Cools, A.R.
2007Adrenergic receptors in the nucleus accumbens shell differentially modulate dopamine and acetylcholine receptor-mediated turning behaviour.Ikeda, H.; Moribe, S.; Sato, M.; Kotani, A.; Koshikawa, N.; Cools, A.R.
2006De maakbare hersenen : zin en onzinCools, A.R.
2006Differences in the cellular mechanism underlying the effects of amphetamine on prepulse inhibition in apomorphine-susceptible and apomorphine-unsusceptibleElst, M.C.J. van der; Wunderink, Y.S.; Ellenbroek, A.A.; Cools, A.R.
2006Distinct kinds of novelty processing differentially increase extracellular dopamine in different brain regions.Leonibus, E. de; Verheij, M.M.M.; Mele, A.; Cools, A.R.
2006Effects of chronic treatment with fluvoxamine and paroxetine during adolescence on serotonin-related behavior in adult male rats.Jong, T.R. de; Snaphaan, L.J.A.E.; Pattij, T.; Veening, J.G.; Waldinger, M.D.; Cools, A.R.; Olivier, B.
2006Cocaine strongly reduces prepulse inhibition in apomorphine-susceptible rats, but not in apomorphine-unsusceptible rats: regulation by dopamine D2 receptors.Elst, M.C.J. van der; Ellenbroek, B.A.; Cools, A.R.
2006Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis.Smits, B.M.; Mudde, J.B.; Belt, J. van de; Verheul, M.; Olivier, J.; Homberg, J.R.; Guryev, V.; Cools, A.R.; Ellenbroek, B.A.; Plasterk, R.H.; Cuppen, E.
2006Serotonin and the neurobiology of the ejaculatory threshold.Jong, T.R. de; Veening, J.G.; Waldinger, M.D.; Cools, A.R.; Olivier, B.

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