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| Full Text | Issue Date | Title | Author(s) |  | 2012 | NucleaRDB: information system for nuclear receptors. | Vroling, B.; Thorne, D.; McDermott, P.; Joosten, H.J.; Attwood, T.K.; Pettifer, S.; Vriend, G. |
| | 2012 | CING: an integrated residue-based structure validation program suite | Doreleijers, J.; Sousa da Silva, A.W.; Krieger, E.; Nabuurs, S.B.; Spronk, C.A.E.M.; Stevens, T.J.; Vranken, W.F.; Vriend, G.; Vuister, G.W. |
| | 2012 | NRG-CING: integrated validation reports of remediated experimental biomolecular NMR data and coordinates in wwPDB. | Doreleijers, J.; Vranken, W.F.; Schulte, C.; Markley, J.L.; Ulrich, E.L.; Vriend, G.; Vuister, G.W. |
| | 2012 | The role of the second and third extracellular loops of the adenosine A1 receptor in activation and allosteric modulation. | Peeters, M.C.E.; Wisse, L.E.; Dinaj, A.; Vroling, B.; Vriend, G.; IJzerman, A.P. |
| | 2012 | A novel COCH mutation associated with autosomal dominant nonsyndromic hearing loss disrupts the structural stability of the vWFA2 domain | Cho, H.J.; Park, H.J.; Trexler, M.; Venselaar, H.; Lee, K.Y.; Robertson, N.G.; Baek, J.I.; Kang, B.S.; Morton, C.C.; Vriend, G.; Patthy, L.; Kim, U.K. |
| | 2012 | Dominant missense mutations in ABCC9 cause Cantu syndrome. | Harakalova, M.; Harssel, J.J. van; Terhal, P.A.; Lieshout, S. van; Duran, K.; Renkens, I.; Amor, D.J.; Wilson, L.C.; Kirk, E.P.; Turner, C.L.; Shears, D.; Garcia-Minaur, S.; Lees, M.M.; Ross, A.; Venselaar, H.; Vriend, G.; Takanari, H.; Rook, M.B.; Heyden, M.A. van der; Asselbergs, F.W.; Breur, H.M.; Swinkels, M.E.; Scurr, I.J.; Smithson, S.F.; Knoers, N.V.A.M.; Smagt, J.J. van der; Nijman, IJ; Kloosterman, W.P.; Haelst, M.M. van; Haaften, G. van; Cuppen, E. |
| | 2012 | Exploring protein dynamics space: the dynasome as the missing link between protein structure and function. | Hensen, U.; Meyer, T.; Haas, J.; Rex, R.; Vriend, G.; Grubmuller, H. |
| | 2012 | A molecular switch driving inactivation in the cardiac k(+) channel HERG. | Kopfer, D.A.; Hahn, U.; Ohmert, I.; Vriend, G.; Pongs, O.; Groot, B.L. de; Zachariae, U.G. |
| | 2012 | Drug design for ever, from hype to hope. | Seddon, G.; Lounnas, V.; McGuire, R.; Bergh, T. van den; Bywater, R.P.; Oliveira, L.; Vriend, G. |
| | 2012 | Antibody engineering reveals the important role of J segments in the production efficiency of llama single-domain antibodies in Saccharomyces cerevisiae. | Gorlani, A.; Hulsik, D.L.; Adams, H; Vriend, G.; Hermans, P.; Verrips, T. |
| | 2012 | AsteriX: a Web server to automatically extract ligand coordinates from figures in PDF articles. | Lounnas, V.; Vriend, G. |
 | 2011 | Integrating GPCR-specific information with full text articles | Vroling, B.; Thorne, D.; McDermott, P.; Attwood, T.K.; Vriend, G.; Pettifer, S. |
 | 2011 | Systematic generation of in vivo G protein-coupled receptor mutants in the rat | Boxtel, R. van; Vroling, B.; Toonen, P.; Nijman, I.J.; Roekel, H. van; Verheul, M.; Baakman, C.A.B.; Guryev, V.; Vriend, G.; Cuppen, E. |
| | 2011 | GPCRDB: information system for G protein-coupled receptors | Vroling, B.; Sanders, M.; Baakman, C.A.B.; Borrmann, A.; Verhoeven, S.; Klomp, J.; Oliveira, L.; Vlieg, J. de; Vriend, G. |
| | 2011 | A series of PDB related databases for everyday needs | Joosten, R.P.; te Beek, T.A.; Krieger, E.; Hekkelman, M.L.; Hooft, R.W.; Schneider, R.; Sander, C.; Vriend, G. |
| | 2011 | A new generation of crystallographic validation tools for the protein data bank | Read, R.J.; Adams, P.D.; Arendall, W.B., 3rd; Brunger, A.T.; Emsley, P.; Joosten, R.P.; Kleywegt, G.J.; Krissinel, E.B.; Lutteke, T.; Otwinowski, Z.; Perrakis, A.; Richardson, J.S.; Sheffler, W.H.; Smith, J.L.; Tickle, I.J.; Vriend, G.; Zwart, P.H. |
| | 2011 | Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis | Laar, I.M. van de; Oldenburg, R.A.; Pals, G.; Roos-Hesselink, J.W.; Graaf, B.M. de; Verhagen, J.M.; Hoedemaekers, Y.M.; Willemsen, R.; Severijnen, L.A.; Venselaar, H.; Vriend, G.; Pattynama, P.M.; Collee, M.; Majoor-Krakauer, D.; Poldermans, D.; Frohn-Mulder, I.M.; Micha, D.; Timmermans, J.; Hilhorst-Hofstee, Y.; Bierma-Zeinstra, S.M.; Willems, P.J.; Kros, J.M.; Oei, E.H.; Oostra, B.A.; Wessels, M.W.; Bertoli-Avella, A.M. |
| | 2010 | Synthesis of covalently linked enzyme dimers | Schoffelen, S.; Schobers, L.; Venselaar, H.; Vriend, G.; Hest, J.C.M. van |
| | 2010 | WIWS: a protein structure bioinformatics Web service collection. | Hekkelman, M.L.; Beek, T.A.H. te; Pettifer, S.R.; Thorne, D.; Attwood, T.K.; Vriend, G. |
| | 2010 | Homology modelling and spectroscopy, a never-ending love story. | Venselaar, H.; Joosten, R.P.; Vroling, B.; Baakman, C.A.; Hekkelman, M.L.; Krieger, E.; Vriend, G. |
| | 2010 | Protein structure analysis of mutations causing inheritable diseases : an e-science approach with life scientist friendly interfaces | Venselaar, H.; Beek, T.A.H. te; Kuipers, R.K.P.; Hekkelman, M.L.; Vriend, G. |
| | 2010 | 3DM: systematic analysis of heterogeneous superfamily data to discover protein functionalities. | Kuipers, R.K.P.; Joosten, H.J.; Berkel, W.J. van; Leferink, N.G.; Rooijen, E.; Ittmann, E.; Zimmeren, F. van; Jochens, H.; Bornscheuer, U.; Vriend, G.; Santos, V.A. dos; Schaap, P.J. |
| | 2010 | The moonlighting function of pyruvate carboxylase resides in the non-catalytic end of the TIM barrel. | Huberts, D.H.; Venselaar, H.; Vriend, G.; Veenhuis, M.; Klei, I.J. van der |
| | 2010 | The EMBRACE web service collection. | Pettifer, S.; Ison, J.; Kalas, M.; Thorne, D.; McDermott, P.; Jonassen, I.; Liaquat, A.; Fernandez, J.M.; Rodriguez, J.M.; Pisano, D.G.; Blanchet, C.; Uludag, M.; Rice, P.; Bartaseviciute, E.; Rapacki, K.; Hekkelman, M.L.; Sand, O.; Stockinger, H.; Clegg, A.B.; Bongcam-Rudloff, E.; Salzemann, J.; Breton, V.; Attwood, T.K.; Cameron, G.; Vriend, G. |
| | 2010 | GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base. | Khelashvili, G.; Dorff, K.; Shan, J.; Camacho-Artacho, M.; Skrabanek, L.; Vroling, B.; Bouvier, M.; Devi, L.A.; George, S.R.; Javitch, J.A.; Lohse, M.J.; Milligan, G.; Neubig, R.R.; Palczewski, K.; Parmentier, M.; Pin, J.P.; Vriend, G.; Campagne, F.; Filizola, M. |
| | 2010 | Toward a consensus model of the HERG potassium channel. | Stary, A.; Wacker, S.J.; Boukharta, L.; Zachariae, U.G.; Karimi-Nejad, Y.; Aqvist, J.; Vriend, G.; Groot, B.L. de |
| | 2009 | An active registry for bioinformatics web services. | Pettifer, S.; Thorne, D.; McDermott, P.; Attwood, T.; Baran, J.; Bryne, J.C.; Hupponen, T.; Mowbray, D.; Vriend, G. |
| | 2009 | PDB_REDO: automated re-refinement of X-ray structure models in the PDB. | Joosten, R.P.; Salzemann, J.; Bloch, V.; Stockinger, H.; Berglund, A.; Blanchet, C.; Bongcam-Rudloff, E.; Combet, C.; Da Costa, A.L.; Deleage, G.; Diarena, M.; Fabbretti, R.; Fettahi, G.; Flegel, V.; Gisel, A.; Kasam, V.; Kervinen, T.; Korpelainen, E.; Mattila, K.; Pagni, M.; Reichstadt, M.; Breton, V.; Tickle, I.J.; Vriend, G. |
| | 2009 | Correlated mutation analyses on super-family alignments reveal functionally important residues. | Kuipers, R.K.P.; Joosten, H.J.; Verwiel, E.; Paans, S.; Akerboom, J.; Oost, J. van der; Leferink, N.G.; Berkel, W.J. van; Vriend, G.; Schaap, P.J. |
| | 2009 | Re-refinement from deposited X-ray data can deliver improved models for most PDB entries. | Joosten, R.P.; Womack, T.; Vriend, G.; Bricogne, G. |
| | 2009 | Human dectin-1 deficiency and mucocutaneous fungal infections. | Ferwerda, E.B.; Ferwerda, G.; Plantinga, T.S.; Willment, J.A.; Spriel, A.B. van; Venselaar, H.; Elbers, C.C.; Johnson, M.D.; Cambi, A.; Huysamen, C.; Jacobs, L.; Jansen, T.J.G.; Verheijen, K.; Masthoff, L.; Morre, S.A.; Vriend, G.; Williams, D.L.; Perfect, J.R.; Joosten, L.A.B.; Wijmenga, C.; Meer, J.W.M. van der; Adema, G.J.; Kullberg, B.J.; Brown, G.D.; Netea, M.G. |
| | 2009 | The NMR restraints grid at BMRB for 5,266 protein and nucleic acid PDB entries. | Doreleijers, J.F.; Vranken, W.F.; Schulte, C.; Lin, J.; Wedell, J.R.; Penkett, C.J.; Vuister, G.W.; Vriend, G.; Markley, J.L.; Ulrich, E.L. |
| | 2009 | Clinical and molecular characterizations of novel POU3F4 mutations reveal that DFN3 is due to null function of POU3F4 protein. | Lee, H.K.; Song, M.H.; Kang, M.; Lee, J.T.; Kong, K.A.; Choi, S.J.; Lee, K.Y.; Venselaar, H.; Vriend, G.; Lee, W.S.; Park, H.J.; Kwon, T.K.; Bok, J.; Kim, U.K. |
| | 2008 | Mutations of ESRRB encoding estrogen-related receptor beta cause autosomal-recessive nonsyndromic hearing impairment DFNB35. | Collin, R.W.J.; Kalay, E.; Tariq, M.; Peters, T.A.; Zwaag, B. van der; Venselaar, H.; Oostrik, J.; Lee, K.; Ahmed, Z.M.; Caylan, R.; Li, Y.; Spierenburg, H.A.; Eyupoglu, E.; Heister, A.; Riazuddin, Saima; Bahat, E.; Ansar, M.; Arslan, S.; Wollnik, B.; Brunner, H.G.; Cremers, C.W.R.J.; Karaguzel, A.; Ahmad, W.; Cremers, F.P.M.; Vriend, G.; Friedman, T.B.; Riazuddin, Sheikh; Leal, S.M.; Kremer, H. |
| | 2008 | 3D-Fun: predicting enzyme function from structure. | Grotthuss, M. von; Plewczynski, D.; Vriend, G.; Rychlewski, L. |
| | 2008 | The molecular mechanism of toxin-induced conformational changes in a potassium channel : relation to C-type inactivation | Zachariae, U.; Schneider, R.; Velisetty, P.; Lange, A.; Seeliger, D.; Wacker, S.J.; Karimi-Nejad, Y.; Vriend, G.; Becker, S.; Pongs, O.; Baldus, M.; Groot, B.L. de |
| | 2008 | Missense mutations in POU4F3 cause autosomal dominant hearing impairment DFNA15 and affect subcellular localization and DNA binding. | Collin, R.W.J.; Chellappa, R.; Pauw, R.J.; Vriend, G.; Oostrik, J.; Drunen, W van; Huygen, P.L.; Admiraal, R.; Hoefsloot, L.H.; Cremers, F.P.M.; Xiang, M.; Cremers, C.W.R.J.; Kremer, H. |
| | 2008 | Tracing evolutionary pressure. | Ye, K.; Vriend, G.; IJzerman, A.P. |
| | 2007 | PDB improvement starts with data deposition | Joosten, R.P.; Vriend, G. |
| | 2007 | The use of in vitro peptide binding profiles and in silico ligand-receptor interaction profiles to describe ligand-induced conformations of the retinoid X receptor alpha ligand-binding domain | Folkertsma, S.; Noort, P.I.; Heer, A.; Carati, P.; Brandt, R.; Visser, A.; Vriend, G.; Vlieg, J. de |
| | 2007 | Stabilization of peptide fibrils by hydrophobic interaction | Meijer, J.T.; Roeters, M.; Viola, V.; Lowik, D.W.P.M.; Vriend, G.; Hest, J.C.M. van |
| | 2007 | Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base | Skrabanek, L.; Murcia, M.; Bouvier, M.; Devi, L.; George, S.R.; Lohse, M.J.; Milligan, G.; Neubig, R.; Palczewski, K.; Parmentier, M.; Pin, J.P.; Vriend, G.; Javitch, J.A.; Campagne, F.; Filizola, M. |
| | 2006 | Integrins of Anopheles gambiae and a putative role of a new beta integrin, BINT2, in phagocytosis of E. coli | Moita, L.F.; Vriend, G.; Mahairaki, V.; Louis, C.; Kafatos, F.C. |
| | 2006 | GRIS: glycoprotein-hormone receptor information system | Durme, J. van; Horn, F.; Costagliola, S.; Vriend, G.; Vassart, G. |
| | 2006 | Traditional biomolecular structure determination by NMR spectroscopy allows for major errors | Nabuurs, S.B.; Spronk, C.A.E.M.; Vuister, G.W.; Vriend, G. |
| | 2006 | A text-mining analysis of the human phenome | Driel, M.A. van; Bruggeman, J.; Vriend, G.; Brunner, H.G.; Leunissen, J.A.M. |
| | 2006 | A text-mining analysis of the human phenome | Driel, M.A. van; Bruggeman, J.; Vriend, G.; Brunner, H.G.; Leunissen, J.A.M. |
| | 2006 | Costs and benefits of processivity in enzymatic degradation of recalcitrant polysaccharides | Horn, S.J.; Sikorski, P.; Cederkvist, J.B.; Vaaje-Kolstad, G.; Sorlie, M.; Synstad, B.; Vriend, G.; Varum, K.M.; Eijsink, V.G. |
| | 2006 | Fast empirical pKa prediction by Ewald summation | Krieger, E.; Nielsen, J.E.; Spronk, C.A.E.M.; Vriend, G. |
| | 2006 | Correcting ligands, metabolites, and pathways | Ott, M.A.; Vriend, G. |
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